Asymmetrical neutral milk hotel offal

Paraplacodus broilii is an extinct placodont sauropterygian from the Middle Triassic epoch, from the Anisian until Ladinian stages. The fossils were uncovered in Northern Italy and the species was named in 1931 by Bernhard Peyer. Paraplacodus means \"Almost Placodus\", in reference to its similarity to Placodus.

SR-14968 is a drug which acts as a biased agonist at the μ-opioid receptor, selective for activation of the G-protein signalling pathway over β-arrestin 2 recruitment. It is closely related to other compounds such as SR-17018 although it is more potent and is a fully efficacious agonist. SR-14968 shows robust biased agonist activity in vitro, but in animal studies in vivo behaves more like a typical opioid agonist and will still produce respiratory suppression at higher doses although it has a wider safety profile compared to fentanyl. Compounds of this class are under development as potential analgesic medications with lower risk of overdose and drug dependence compared to traditional opioid drugs.